Saturday, May 7, 2011

LOW-FAT DIETARY ADVICE PRIMARILY RESPONSIBLE ALZHEIMER'S DISEASE?

Population studies in tropical cultures that consume coconuts seldom see diseases like Alzheimer's Disease.
The harm of low-fat high-carbohydrate diets in cholesterol uptake in the brain
 The role of diet in Alzheimer’s disease (AD) is continuing to make strong headlines here in 2011 as hundreds of millions of dollars in drug research have yet to produce any significant cure. One of the latest studies published appeared in the European Journal of Internal Medicine: “Nutrition and Alzheimer's disease: The detrimental role of a high carbohydrate diet”.
 
The authors of this study have noted how researchers have begun to direct their energies towards understanding the earlier stages of AD, since drug research in later stages has not been very successful. They note that several researchers have noticed a strong correlation between insulin resistance in the brain and early AD, suggesting that AD might be considered a neuroendocrine disorder of the brain or so-called “type 3 diabetes.” Other observations have noted an association of AD with mitochondrial dysfunction, which is also common in Parkinson's disease, and amyotrophic lateral sclerosis (ALS).

But the authors’ main conclusions regarding the early causes of AD center around the transport of cholesterol from the blood stream to the brain. They state that there is mounting evidence which suggests that a defect in cholesterol metabolism in the brain may play an important role in AD. They give a nice summary of the brain’s dependency on cholesterol:
The brain represents only 2% of the body's total mass, but contains 25% of the total cholesterol. Cholesterol is required everywhere in the brain as an antioxidant, an electrical insulator (in order to prevent ion leakage), as a structural scaffold for the neural network, and a functional component of all membranes. Cholesterol is also utilized in the wrapping and synaptic delivery of the neurotransmitters. It also plays an important role in the formation and functioning of synapses in the brain.
They point to several studies that show a lack of cholesterol present in the brains of AD patients which is so vital for several functions, and also note that other studies show this cholesterol deficiency in dementia and Parkinson's disease. In contrast, high cholesterol levels are positively correlated with longevity in people over 85 years old, and in some cases has been shown to be associated with better memory function and reduced dementia.
 
The authors go on to explain that the lipid theory of heart disease started by the work of Ancel Keys in the 1960s led to dietary beliefs that cholesterol was to be avoided in the diet, and with that belief came the “over-zealous prescription of cholesterol-reducing medications over the same decades in which there has been a parallel rise in AD prevalence.”

How Coconut Oil Can Help
 
Coconut oil ... is highly saturated, and in its natural unrefined form has a shelf life of more than 2 years. Unlike unsaturated oils, it is not prone to oxidation.
 
Also, the study from the European Journal of Internal Medicine referenced above notes that Alzheimer’s, Parkinson's disease, and amyotrophic lateral sclerosis (ALS) all have an association with mitochondrial dysfunction. A study published in 2010 used coconut oil to show that a diet enriched in the saturated fatty acids of coconut oil offered strong advantages for the protection against oxidative stress in heart mitochondria.
 
Much research is also being uncovered now on the advantages of high HDL cholesterol levels, besides the study we mentioned above in direct relation to Alzheimer’s. A study appearing in the American Journal of Cardiology earlier this month (February 2011) showed that the higher men’s HDL cholesterol levels, the longer they lived and the more likely it was that they would reach the age of 85.4 A diet with adequate amounts of saturated fat is essential to keeping HDL high cholesterol levels. Those with deficiencies and suffering from neurological disorders need to consider a diet that is high in saturated fat, in stark contrast to the mainstream dietary advice for low-fat diets that might be causing many of these late-in-life diseases.
 
To read the rest of the article, which explains how coconut oil aids in the treatment of AD and the reversal of its symptoms, click here.

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